Screening tests for fetal health (double marker, triple marker and quad marker tests)
Dear patients, Any laboratory tests must be accompanied by genetic records, ultrasound results, and a list of prescribed medicines in order to complete the specialty in the laboratory.
One of the main concerns during pregnancy is the lack of knowledge about the health of the fetus during the 9-month period of pregnancy, which has been a major effort to minimize these concerns through prenatal care and testing. Screening tests are examples of tests that are performed to check the status of the embryo for chromosomal abnormalities in the first and second trimester of pregnancy. Screening tests show the chance or probability that the fetus has one of several specific illnesses. In fact, this test certainly can not determine the presence or absence of a complication in the baby, but only predicts the risk. If the result of the test is positive, this means that the probability of a defect is higher than others. For this reason, the doctor may perform diagnostic tests for the pregnant woman to ensure the safety of the fetus. In contrast, if the result of the screening test is negative, the probability of a fetal complication is so low that it does not require follow up. However, in this case there is also no assurance or assurance regarding the health of the baby. The advantage of screening tests is that this method is non-invasive and does not entail any risk of abortion and does not harm the fetus.
Screening of fetal abnormalities in the first trimester of pregnancy
Screening for the first trimester of pregnancy is a combined test including maternal and ultrasound tests along with the determination of NT. The time of screening for the first trimester is 10 weeks and 5 days to 13 weeks and 5 days of pregnancy.
This test consists of a blood test (in which two biochemical parameters of PAPP-A and Free βHCG are measured in the mother’s blood) and an ultrasound. In NT ultrasound, the accumulation of fluid behind the neck of the embryo is measured. In fact, an increase in this area may be a symptom of Down syndrome or Trysomy syndrome. The total results of NT ultrasound, maternal blood test, and maternal age are analyzed and interpreted together and a number is obtained, according to which the next step can be decided.
Based on the results of the first trimester screening, pregnant women are divided into three categories: high risk, moderate, and low risk. Those who are at low risk do not need to undergo another screening or diagnostic test, and only women with a moderate risk are candidates for screening tests for the second stage. High-risk women are advised to perform CVS diagnostic tests (pairwise sampling) or amniocentesis.